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Jin Chen Selected Research

Paclitaxel (Taxol)

12/2023Complement Receptor C3aR1 Contributes to Paclitaxel-Induced Peripheral Neuropathic Pain in Mice and Rats.
9/2020Dual-Responsive Dual-Drug-Loaded Bioinspired Polydopamine Nanospheres as an Efficient Therapeutic Nanoplatform against Drug-Resistant Cancer Cells.
6/2020Phytochemical Curcumin-Coformulated, Silver-Decorated Melanin-like Polydopamine/Mesoporous Silica Composites with Improved Antibacterial and Chemotherapeutic Effects against Drug-Resistant Cancer Cells.
1/2018Mesenchymal stem cells drive paclitaxel resistance in ErbB2/ErbB3-coexpressing breast cancer cells via paracrine of neuregulin 1.
10/2012Transport, metabolism, cytotoxicity and effects of novel taxanes on the cell cycle in MDA-MB-435 and NCI/ADR-RES cells.
6/2008Design, synthesis, and biological evaluation of new-generation taxoids.
7/2005Transport and cytotoxicity of paclitaxel, docetaxel, and novel taxanes in human breast cancer cells.

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Jin Chen Research Topics

Disease

188Neoplasms (Cancer)
04/2024 - 02/2002
46Neoplasm Metastasis (Metastasis)
04/2024 - 02/2002
40Inflammation (Inflammations)
12/2023 - 02/2002
30Infections
04/2024 - 01/2005
23Breast Neoplasms (Breast Cancer)
01/2024 - 06/2002
22Hepatocellular Carcinoma (Hepatoma)
08/2023 - 07/2012
18Carcinogenesis
12/2023 - 09/2003
17Lung Neoplasms (Lung Cancer)
11/2023 - 05/2005
16Heart Failure
12/2023 - 06/2005
15Fibrosis (Cirrhosis)
01/2024 - 07/2007
11Non-alcoholic Fatty Liver Disease
04/2024 - 12/2014
11Sepsis (Septicemia)
06/2023 - 08/2009
11Hearing Loss (Hearing Impairment)
04/2022 - 01/2011
11Carcinoma (Carcinomatosis)
09/2021 - 06/2002
10Myocardial Infarction
03/2024 - 10/2010
9Pain (Aches)
12/2023 - 05/2008
9Osteosarcoma (Osteogenic Sarcoma)
12/2021 - 09/2008
8Acne Vulgaris
04/2024 - 02/2016
8Wounds and Injuries (Trauma)
10/2023 - 06/2003
8Hypoxia (Hypoxemia)
05/2023 - 06/2016
8Melanoma (Melanoma, Malignant)
01/2023 - 01/2004
7Epilepsy (Aura)
05/2024 - 03/2015
7Glioma (Gliomas)
02/2024 - 01/2015
7Atherosclerosis
12/2023 - 03/2012
7Stroke (Strokes)
11/2023 - 06/2016
7Necrosis
10/2023 - 02/2009
7Body Weight (Weight, Body)
11/2022 - 12/2007
6Hypertension (High Blood Pressure)
01/2024 - 01/2012
6Colorectal Neoplasms (Colorectal Cancer)
11/2023 - 05/2008
6Cognitive Dysfunction
10/2023 - 08/2020
6Ovarian Neoplasms (Ovarian Cancer)
10/2023 - 06/2008
6Liver Neoplasms (Liver Cancer)
11/2022 - 02/2010
6Type 2 Diabetes Mellitus (MODY)
10/2022 - 11/2013
6Obesity
10/2022 - 02/2015
6Hemorrhage
01/2021 - 09/2014
6Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
11/2020 - 05/2014
6Human Influenza (Influenza)
01/2019 - 12/2010
6Squamous Cell Carcinoma (Epidermoid Carcinoma)
01/2019 - 01/2012
6Squamous Cell Carcinoma of Head and Neck
08/2018 - 05/2009
6Hyperlipoproteinemia Type I (Lipoprotein Lipase Deficiency, Familial)
12/2017 - 02/2015
5Brain Injuries (Brain Injury)
03/2024 - 02/2010
5COVID-19
11/2023 - 10/2020
5Adenocarcinoma
10/2023 - 11/2005
5Chronic Obstructive Pulmonary Disease (COPD)
07/2023 - 03/2010
5Insulin Resistance
01/2023 - 12/2014

Drug/Important Bio-Agent (IBA)

62Proteins (Proteins, Gene)FDA Link
04/2024 - 06/2002
31Biomarkers (Surrogate Marker)IBA
03/2024 - 01/2005
21LigandsIBA
10/2023 - 02/2002
20LipidsIBA
01/2024 - 04/2002
19CytokinesIBA
01/2024 - 09/2003
16Messenger RNA (mRNA)IBA
01/2024 - 03/2009
15Phosphotransferases (Kinase)IBA
11/2021 - 09/2003
14Therapeutic UsesIBA
01/2023 - 01/2012
14EphA2 ReceptorIBA
11/2020 - 10/2002
13RNA (Ribonucleic Acid)IBA
04/2024 - 12/2014
13CateninsIBA
05/2023 - 01/2015
13EphrinsIBA
11/2016 - 02/2002
12VaccinesIBA
03/2024 - 01/2013
12Eph Family Receptors (Eph Receptors)IBA
11/2016 - 02/2002
11Doxorubicin (Adriamycin)FDA LinkGeneric
01/2023 - 07/2005
11Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2020 - 11/2002
10MicroRNAs (MicroRNA)IBA
03/2024 - 03/2011
10AntigensIBA
01/2024 - 09/2005
10EnzymesIBA
01/2023 - 02/2010
10Long Noncoding RNAIBA
01/2023 - 12/2014
10CurcuminIBA
01/2021 - 07/2014
10pradigastatIBA
10/2017 - 02/2015
9DNA (Deoxyribonucleic Acid)IBA
01/2024 - 11/2013
9Triglycerides (Triacylglycerol)IBA
10/2022 - 11/2013
9EphA1 Receptor (Eph Receptor)IBA
11/2016 - 02/2002
8Glucose (Dextrose)FDA LinkGeneric
11/2023 - 10/2010
8Particulate MatterIBA
07/2023 - 03/2016
8C-Reactive ProteinIBA
01/2023 - 12/2007
8CholesterolIBA
06/2020 - 12/2007
8tyrosine receptor (receptor, tyrosine)IBA
01/2016 - 09/2003
7Immune Checkpoint InhibitorsIBA
04/2024 - 01/2019
7Paclitaxel (Taxol)FDA LinkGeneric
12/2023 - 07/2005
7Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
10/2022 - 09/2003
7Interleukin-6 (Interleukin 6)IBA
10/2020 - 06/2009
7Insulin (Novolin)FDA Link
06/2020 - 10/2010
7AutoantibodiesIBA
06/2020 - 06/2005
7Ephrin-A1 (Ephrin A1)IBA
01/2020 - 10/2002
6Hemoglobins (Hemoglobin)IBA
12/2023 - 03/2014
6Anti-Bacterial Agents (Antibiotics)IBA
10/2023 - 09/2012
6Small Interfering RNA (siRNA)IBA
10/2023 - 11/2006
6AcidsIBA
10/2023 - 08/2004
6LipopolysaccharidesIBA
06/2023 - 02/2016
6tropifexorIBA
11/2022 - 01/2020
6Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
12/2017 - 09/2003
6Tyrosine (L-Tyrosine)FDA Link
11/2016 - 01/2004
5Blood Glucose (Blood Sugar)IBA
01/2024 - 01/2020
5Transcription Factors (Transcription Factor)IBA
11/2023 - 01/2016
5AluminumIBA
04/2023 - 07/2020

Therapy/Procedure

66Therapeutics
05/2024 - 06/2003
21Drug Therapy (Chemotherapy)
01/2024 - 04/2002
10Immunotherapy
04/2024 - 08/2010
9Radiofrequency Ablation
12/2023 - 11/2012
8Radiotherapy
07/2023 - 03/2015
7Transplantation
01/2022 - 12/2015
6Aftercare (After-Treatment)
01/2023 - 11/2017